The Choir of Exeter College at the University of Oxford consists of 24 singers and is under the direction of Christopher Holman. Originally established as a choral foundation of men and boys, the Choir was re-founded in 1995 as a mixed voice ensemble, and since has established itself as one of the leading student ensembles in the United Kingdom. The Choir sings four services per week during the University's term, presenting a vast body of repertoire from plainchant and medieval polyphony to newly composed works, and everything in between. The ensemble is also a strong advocate of music by marginalised composers, having performed the modern-day UK premieres of choral works by Fanny Hensel, Thomas King Ekundayo Phillips, Raffaella Aleotti, José Maurício Nunes Garcia, and Lili'uokalani of Hawai'i.

The Choir has collaborated with the Oxford Philharmonia, The Oxford Lieder Festival, the Oxford Bach Soloists, and The Brandenburg Festival in London, and maintains an active schedule of concerts, international tours, and recordings. In 2021 the Choir was featured as part of the Derwent Valley Mills UNESCO World Heritage Site's multimedia project 'Spin a Tale' with Constella OperaBallet. The Choir is also a regular guest at major cathedrals in the UK, having most recently sung at Westminster Abbey, with appearances scheduled at St Paul's Cathedral in London, and Winchester and Hereford Cathedrals. The Choir has also been broadcast on BBC Radio 3, Radio 4, and episodes of Inspector Morse and Endeavour.